Restriction fragment length polymorphism or RFLP analyses the patterns in DNA cleaved from different organisms. The similarities in the pattern help researchers differentiate one species from another or a strain from another.
RFLP is one of the first techniques used in genetic mapping and forensic sciences. It is a kind of polymorphism, which are inherited differences in DNA sequences. It is found in over 1% of the average population. At Yaazh, we use restriction enzymes to digest the sample DNA and study the length of fragments produced.
RFLP is still widely used to map the human genome and study genetic diseases. Some other areas where our RFLP services can be relied upon are
In forensics, to investigate the source of DNA in a criminal case or to study paternity.
In genetic mapping, to measure the rate of recombination by studying the centimorgan distance between RFLP loci.
In mutation detections, to determine the status of a disease in a person.