UPLC Analysis Services In India
High-Resolution Ultra Performance Liquid Chromatography for robust analytical testing.
What is UPLC?
UPLC (Ultra Performance Liquid Chromatography) is an advanced liquid chromatography technique that utilizes columns packed with particles less than 2 µm in diameter. This allows operation at much higher pressures than traditional HPLC (up to 15,000 psi).
- 3–10× faster analysis time
- 2–5× higher resolution and peak capacity
- Improved sensitivity and reduced solvent consumption
- Better separation of complex mixtures
Extending Our Capacities With UPLC
Putting any advanced technology to good use is the USP of our genomics services. We deliver mission-critical, scalable solutions with UPLC.
Qualitative analysis for individual compounds
Quantitative analysis for trace amounts
Quantitation of polymer additives
Mapping of glycopeptides and peptides
Testing of impurities and surfactant analysis
Capabilities & Services
Advanced UPLC Systems
- • Agilent 1290 Infinity II UPLC System
- • Waters Acquity UPLC H-Class & I-Class Systems
- • Binary and Quaternary solvent delivery systems
- • Photodiode Array (PDA), UV-Vis, Fluorescence detectors
- • Sub-2 µm particle columns (BEH, CSH, HSS technology)
Key UPLC Services We Offer
- • Pharmaceutical Assay & Content Uniformity
- • Impurity Profiling – Process, degradation, genotoxic impurities
- • Stability-Indicating Method Development per ICH Q1A–Q1E
- • Full Analytical Validation per ICH Q2(R1), USP, FDA guidelines
- • Bioanalytical Method Development for pharmacokinetics
UPLC vs HPLC
| Parameter | HPLC | UPLC |
|---|---|---|
| Particle Size | 3–5 µm | <2 µm (typically 1.7 µm) |
| Operating Pressure | Up to 6000 psi | Up to 15000 psi |
| Analysis Time | 15–60 minutes | 2–10 minutes |
| Resolution | Good | Excellent (2–5× higher peak capacity) |
| Sensitivity | Standard | 3–5× higher |
Our UPLC Workflow
From consultation to routine analysis and reporting.
Project Consultation
Understanding regulatory requirements, analyte properties, and matrix challenges
Sample Preparation
Optimized extraction and clean-up procedures for complex matrices
Method Development
Systematic optimization of column chemistry, mobile phase, flow rate, and detection
Analysis & Reporting
High-throughput analysis with detailed chromatograms and compliant reports
Ready for High-Resolution Analysis?
State-of-the-art UPLC systems with sub-2 µm column technology for fast, compliant, and cost-effective solutions.
Request UPLC Analysis Quote