GC-MS Analysis Services
Residual Solvents, Volatiles & Unknown Identification
What is GC-MS Analysis?
Gas Chromatography-Mass Spectrometry (GC-MS) combines gas chromatographic separation with mass spectrometric detection for high-resolution analysis of volatile and semi-volatile organics. Compounds are vaporized, separated on a capillary column, ionized, and fragmented to produce unique mass spectra for identification and quantification.
Key strengths: Excellent sensitivity (ppb–ppt range), structural information from fragmentation patterns, and large databases for reliable unknown matching – making GC-MS the gold standard for volatiles.
Our GC-MS Capabilities & Instrumentation
End-to-End Analysis Workflow
Consultation & Method Selection
Free expert advice on sample type, target analytes, and regulatory needs.
Sample Preparation & QC
Headspace vial equilibration, SPME, liquid-liquid extraction; matrix-matched standards.
Method Development
Column/oven program optimization, split/splitless injection tuning, MS parameters.
Analysis & Validation
System suitability, calibration, QC samples, full validation reporting.
Data Processing
Chromatogram/mass spectra review, library matching, quantification, unknown ID.
Key Applications of Our GC-MS Analysis
- Pharmaceuticals – Residual solvents (Class 1–3), process impurities, extractables
- Food & Beverages – Pesticide residues, flavor volatiles, contaminants (PAH, phthalates)
- Environmental – VOCs in water/soil/air, BTEX, organochlorine pesticides
- Forensic & Drug Detection – Volatile drugs, accelerants, poisons
- Herbal & Essential Oils – Volatile profiling, adulteration detection
- Unknown Identification – Mystery samples, off-odor analysis, polymer degradation
GC-MS Advantages & Limitations
- Superior sensitivity & specificity for volatiles/semi-volatiles
- Robust library matching for unknowns
- Quantitative precision for regulatory compliance
- Limited to volatile/thermally stable compounds (non-volatiles need derivatization)
- Matrix interference in complex samples (mitigated by cleanup/headspace)
For non-volatile or polar analytes, explore our LC-MS or HPLC services.
Exclusive Applications
Our robust GC-MS system helps in cracking the most challenging applications in various fields such as:
Pharmaceutical industries.
Forensics department.
Environmental sample analysis.
Food & beverage industry.
Get Started with GC-MS Analysis in India
Need precise GC-MS for residual solvents, volatiles, or unknown identification? Contact Coimbatore’s trusted analytical lab for a personalized quote today.