Frequently Asked Questions – Yaazh Xenomics

Answers to common questions about our genomics services in Coimbatore, Tamil Nadu, India.

General Questions

What is Yaazh Xenomics?

Yaazh Xenomics is Coimbatore's leading affordable genomics and DNA sequencing lab, specializing in NGS, Sanger, Nanopore, DNA barcoding, bioinformatics, and analytical testing for researchers, clinicians, and industries across India.

Where are you located?

Main lab: Module No. 103, TICEL BIOPARK Phase – III, 1st Floor, Maruthamalai Road, Coimbatore – 641046, Tamil Nadu, India.

What turnaround times do you offer?

We provide some of the fastest TAT in India: Sanger sequencing 3–5 days, standard NGS projects 7–14 days (depending on sample volume and complexity).

NGS Sequencing Questions

What platforms do you use for NGS?

We use Illumina (NovaSeq, NextSeq, MiSeq), Oxford Nanopore, MGI, and Thermo platforms for flexible, high-accuracy whole genome, exome, transcriptome, and metagenome sequencing.

Do you provide bioinformatics analysis?

Yes — free standard pipelines plus advanced custom analysis (variant calling, taxonomy classification, visualization, etc.) are included in most projects.

What is NGS and what platforms do you use?

NGS is high-throughput DNA/RNA sequencing for large-scale genomics. We use Illumina (NovaSeq, NextSeq, MiSeq), MGI, Thermo, and Oxford Nanopore platforms for flexible, high-accuracy results.

What types of NGS projects do you handle?

We offer Whole Genome, Exome, Transcriptome (RNA-Seq), Metagenome (16S/Shotgun), Targeted Panels, ChIP-Seq, Methylation, and more for human, plant, animal, microbial samples.

What is your typical TAT and sample requirements for NGS?

Standard projects: 14 –28 days. We accept low-input, FFPE, degraded samples. Minimum DNA/RNA quantities vary (e.g., 1–10 ng for most libraries). Contact us for project-specific requirements.

Sanger Sequencing

What is Sanger sequencing and when should I use it?

Sanger provides accurate, long-read sequencing (up to 1000+ bases/read). Ideal for validation, single-gene analysis, primer walking, difficult templates, or small-scale projects.

What turnaround time do you offer for Sanger?

3–5 working days for standard Sanger sequencing. We handle PCR products, plasmids, and challenging samples with high success rates.

Do you offer primer design or walking services?

Yes – full primer walking and custom sequencing for long amplicons or unknown regions. We design primers and extend coverage step-by-step.

Nanopore Sequencing

What advantages does Nanopore sequencing offer?

Real-time, long-read sequencing (up to Mb lengths) for structural variants, phasing, pathogen ID, antibiotic resistance profiling, metagenomics, and direct RNA sequencing.

What applications do you support with Nanopore?

Metagenomic environmental monitoring, gut microbiome, food safety, bacterial resistance characterization, de novo assembly, and rapid diagnostics.

DNA Barcoding & Microbial Identification

What is DNA barcoding and which markers do you use?

DNA barcoding identifies species using standard genetic markers. We sequence COI (animals), rbcL/matK (plants), ITS (fungi), 16S/18S/23S/26S/28S rRNA (bacteria, archaea, eukaryotes), and more.

What samples do you accept for microbial ID?

Pure cultures, environmental, soil, water, food, clinical samples. We identify bacteria, fungi, algae, yeast, cyanobacteria, and archaea with high accuracy.

Transcriptome / RNA Sequencing

What RNA-Seq services do you provide?

mRNA-Seq, total RNA-Seq, small RNA, lncRNA, meta-transcriptome, gene expression analysis, differential expression, and low-input/FFPE RNA-Seq.

Do you handle degraded or low-quantity RNA?

Yes – specialized protocols for FFPE, low-input, and degraded samples with rRNA depletion or poly-A selection as needed.

Metagenome Sequencing

What is metagenome sequencing and its applications?

Shotgun or amplicon sequencing of microbial communities without culturing. Used for microbiome (gut, soil, water), diversity studies, pathogen detection, and functional analysis.

Do you offer 16S and shotgun metagenomics?

Both: 16S/18S/ITS amplicon for taxonomy, shotgun for functional genes, resistance, and strain-level resolution.

Whole Genome / Exome Sequencing

What is the difference between WGS and WES?

WGS sequences the entire genome (de novo/resequencing). WES targets protein-coding regions (~1–2% of genome) for cost-effective rare disease, cancer, pharmacogenomics studies.

Do you offer human medical genomics?

Yes – clinical exome, cancer panels, rare disease diagnosis, pharmacogenomics with variant annotation and reporting.

Bioinformatics & Data Analysis

What bioinformatics support do you provide?

Free standard pipelines + custom analysis: assembly, annotation, variant calling, differential expression, pathway analysis, phylogenetic trees, visualization.

Can you handle large datasets?

Yes – secure, high-performance analysis for NGS, metagenome, transcriptome data with fast delivery of results.

Analytical Testing Services

What analytical tests do you offer?

HPLC, quality checks for food, nutraceuticals, pharmaceuticals, animal feed, commodities, environmental samples. Compliance-focused testing.

Are your tests accredited?

We follow ISO standards and government regulations for reliable, compliant results.

Have more questions or need a quote? Contact us for personalized assistance.

Have more questions? Contact us for a free consultation.